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Changes in Lung Oscillometry Parameters among Healthy Adults After Inhaled Bronchodilator Use

Bronchodilator Response of Lung Oscillometry Parameters in Healthy Adults: A Pilot Study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/098503
Enrollment
200
Registered
2025-12-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil Control Intervention1: Salbutamol: Eligible individuals will receive 400 micrograms of inhaled sulbutamol after the initial oscillometry to assess the changes after the salbuta

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: i. No prior history of respiratory disease and non smoker

Exclusion criteria

Exclusion criteria: 1. Recent respiratory infection (within 4 weeks). ii. Known cardiac disease or uncontrolled systemic illness. iii.No prior history of respiratory disease (asthma, COPD, bronchiectasis, ILD, pulmonary tuberculosis, etc.). iv. Never-smoker

Design outcomes

Primary

MeasureTime frame
The outcome variables will be whole-breath resistance at 5 Hz (R5), whole-breath reactance at 5 Hz (X5), frequency dependence of resistance (R5 20), resonant frequency (Fres), and reactance area (AX), defined as the integral of reactance between 5 Hz and Fres.Timepoint: The outcome variables will be whole-breath resistance at 5 Hz (R5), whole-breath reactance at 5 Hz (X5), frequency dependence of resistance (R5 20), resonant frequency (Fres), and reactance area (AX), defined as the integral of reactance between 5 Hz and Fres.

Secondary

MeasureTime frame
To compare the variability of oscillometry parameters across different age groups andbetween genders following administration of inhaled bronchodilator. Timepoint: After bronchodilator

Countries

India

Contacts

Public ContactSajal De

All India Institute of Medical Sciences Raaipur

sajalde@yahoo.com9406573825

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026