Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications
Conditions
Interventions
Intervention1: Platelet rich Fibrin application followed by Offloading with Total Contact Cast application: Baseline assessment of Diabetic foot ulcer will be done including recording of dimensions an
Sponsors
ICMR- Investigator Initiated Projects-Small Grant
Eligibility
Inclusion criteria
Inclusion criteria: Patient having Diabetes Mellitus with a foot ulcer. Age of patient between eighteen to seventy five years. Presence of Diabetic Foot ulcer of Wagner staging one and two. Patient should be haemodynamically stable and presence of no fever. Platelet count more than one point five lakh per milliliter blood. Haemoglobin more than eleven gram per decilitre blood. Patient must give consent to take part in study.
Exclusion criteria
Exclusion criteria: Presence of vascular insufficiency- ruled out by Doppler study. Presence of severe Anaemia, Thrombocytopenia, Coagulation disorders, Cardiac disorders, history of Malignancy. Presence of Febrile Illness. Pt on immunosuppressants / anticoagulants. Uncontrolled Diabetes Positive Viral Markers. Under treatment for any Psychiatric issues (failure to comply and follow up). Not willing to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of surface area and volume of the wound Reduction of PUSH score Improvement of wound as per Wagner staging Timepoint: At baseline First week Second week Third week Fourth week Fifth week Sixth week Second month Third month Fourth month Fifth month Sixth month Eighth month Tenth month Twelfth month | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in Quality of life using WHOQOL BREF scale Improvement of lower limb function using Lower Extremity Functional scale Reduction of burden on caregiver using Modified Caregiver strain index scale Timepoint: At baseline First week Second week Third week Fourth week Fifth week Sixth week Second month Third month Fourth month Fifth month Sixth month Eighth month Tenth month Twelfth month | — |
Countries
India
Contacts
Public ContactDr Arvind Kumar Sharma
All India Institute of Medical Sciences, Raebareli
Outcome results
None listed