comparison of two types of drugs ie lignocaine alone and lignocaine with dexamethasone for treatment of pain after propofol injection in patients requiring propofol injection in operation theatre setup

Comparing the Efficacy of lignocaine and combination of lignocaine and dexamethasone during propofol injection pain a randomised control trial - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/098431

Enrollment

160

Registered

2025-12-03

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Lignocaine for treatment of propofol infusion pain: Inj lignocaine will be given at a dose of 0.5mg/kg IV STAT after propofol insuion Control Intervention1: combination of lignocaine an

Eligibility

Inclusion criteria

Inclusion criteria: ASA status I and II Patients requiring intravenous sedation with propofol

Exclusion criteria

Exclusion criteria: patients with allergies to propofol patients on long term corticosteroid therapy patients with history of significant cardiovascular, hepatic or renal disease

Design outcomes

Primary

Measure	Time frame
incidence of pain experienced during propofol injection using 4 pointer verbal rating scale among groups pretreated with lignocaine, combination of lignocaine and dexamethasone with standard treatment of care which is saline and propofolTimepoint: incidence of pain experienced during propofol injection using 4 pointer verbal rating scale among groups pretreated with lignocaine, combination of lignocaine and dexamethasone after 10 second of propofol injection	—

Measure

Time frame

incidence of pain experienced during propofol injection using 4 pointer verbal rating scale among groups pretreated with lignocaine, combination of lignocaine and dexamethasone with standard treatment of care which is saline and propofolTimepoint: incidence of pain experienced during propofol injection using 4 pointer verbal rating scale among groups pretreated with lignocaine, combination of lignocaine and dexamethasone after 10 second of propofol injection

—

Secondary

Measure	Time frame
the intensity of pain using 4 pointer verbal rating scale, hemodynamic parameters and behavioural signs of discomfort among groups pretreated with lignocaine, combination of lignocaine and dexamethasone with standard treatment of care which is saline and propofolTimepoint: 18 months	—

Countries

India

Contacts

Public ContactDr Dewendra Gajbhiye

Guide

dewen26@yahoo.co.in9480977146

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026