Comparison of Standard-Dose and High Dose Mifepristone Regimens for Induction of Labour After Intrauterine Fetal Demise

Comparison of standard and high dose mifepristone regimen for labour induction after foetal demise - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/098372

Enrollment

Registered

2025-12-03

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O048- (Induced) termination of pregnancywith other and unspecified complications

Interventions

Intervention1: Mifepristone in dose 200 mg 12 hourly for 48 hours: Higher doses of mifepristone that is 200 mg 12 hourly for 48 hours as compared to standard dose whic is single 200 mg dose will be us

Eligibility

Inclusion criteria

Inclusion criteria: Singleton pregnancy Confirmed IUFD of 28 weeks or more Longitudinal lie

Exclusion criteria

Exclusion criteria: Patient in whom mifepristone is contraindicated Unknown scar Previous 2 or more LSCS Low lying placenta History of myomectomy Medical surgical disorders

Design outcomes

Primary

Measure	Time frame
Induction delivery intervalTimepoint: Baseline,48 hours,72 hours	—

Secondary

Measure	Time frame
Number of successful vaginal deliveryTimepoint: 48 hours;Reduction in requirement & total dosage of misoprostol usedTimepoint: 72 hours	—

Countries

India

Contacts

Public ContactSanchita Jha

Post Graduate institute of medical education and research

sanchitajha15@gmail.com9059171887

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026