Health Condition 1: 8- Other Procedures
Conditions
Interventions
Intervention1: Denosumab: commercially available denosumab. After placing the denosumab in the bone defect, patient
will be followed for 1 year
Intervention2: Liraglutide: commercially available lira
Sponsors
Kothai abirami T
Eligibility
Inclusion criteria
Inclusion criteria: Patients between 20-40 years of age from both the gender, Periapical lesions involving maxillary and mandibular incisors of strictly endodontic origin, The diameter of the bone defect of 10 -20 mm, Patients willing for voluntary participation & have signed informed consent, Patients with good oral hygiene, Systemically healthy patients.
Exclusion criteria
Exclusion criteria: periodontal tooth with poor prognosis, tooth with pathosis with vertical root fracture, patients with bleeding disorders, patients showing poor oral hygiene maintenance, Patients with use of tobacco or tobacco related products, Pregnant / Lactating patients, Patients with known systemic diseases, Patients with any known allergies, Patients with any known metabolic disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Absence of swelling, pain, pus discharge, sinus opening, Mobility, Tenderness to percussionTimepoint: 1,3,6,9 and 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone density evaluation of the Periapical region was done after surgery using CBCTTimepoint: 6 and 12 months | — |
Countries
India
Contacts
Public ContactKothai abirami T
Tamilnadu Government Dental College and Hospital
Outcome results
None listed