Health Condition 1: I636- Cerebral infarction due to cerebral venous thrombosis, nonpyogenic Health Condition 2: G938- Other specified disorders of brain
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Sponsors
KASTURBA MEDICAL COLLEGE
Eligibility
Inclusion criteria
Inclusion criteria: Radiological diagnosis of CVST by MR venography (MRV) or CT venography (CTV) showing thrombosis of dural venous sinuses and/or cortical veins. Presentation within 14 days of symptom onset.Informed written consent obtained (patient or legally authorized representative).
Exclusion criteria
Exclusion criteria: Prior diagnosis of epilepsy or unprovoked seizures before the CVST event.Patients with iintracranial pathology unrelated to CVST likely to cause seizures (neurocysticercosis, brain tumors, masses, infections, intracranial haemorrhage,cortical dysplasia, brain abscess, meningitis). Traumatic brain injury. Patients who are on anti-epileptic drugs prior.H/o Unprovoked seizures. Refusal or inability to give consent or to complete follow-up.Life expectancy < 48 hours from presentation (moribund patients).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of seizures during hospital stay and follow-up (1 month, 3 months). oSeizures will be documented in terms of type (focal/generalized), frequency, and duration. oEEG confirmation will be performed wherever feasible. Timepoint: Occurrence of seizures during hospital stay and follow-up (1 month, 3 months). oSeizures will be documented in terms of type (focal/generalized), frequency, and duration. oEEG confirmation will be performed wherever feasible. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical predictors: age, sex, presenting symptoms, comorbidities, neurological deficits. Neurological deceit will be assessed by mRS scale, Barthel index, NIHSS scale when were required. Radiological predictors: site of thrombosis, cortical involvement, parenchymal hemorrhage or infarction. VOIS score will be assessed. Laboratory predictors: coagulation profile, serum electrolytes, renal & liver function tests. Seizure associations with treatment & follow-up: correlation between standard management, prophylactic antiepileptics, & seizure occurrence. These measures will help identify risk factors associated with seizure development in CVST patients & provide insights for early intervention. Timepoint: AT ADMISSION , DISCHARGE AND FOLLOW UP (1 month, 3 months) | — |
Countries
India
Contacts
Public ContactDR SHARATH P.S
KASTURBA MEDICAL COLLEGE
Outcome results
None listed