The effect of hypotension prevention drugs on newborns

Comparison of Two Prophylactic Norepinephrine Doses for Prevention of Post-Spinal Hypotension on Umbilical Artery and Vein Blood-Gas Parameters in Patients Undergoing Elective Caesarean Section: A Randomized Controlled Study - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/098339

Enrollment

Registered

2025-12-02

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: NE 0.04: NOREPINEPHRINE 0.04 g/kg/min started as an infusion from the beginning of surgery till the closure via the intravenous route Intervention2: NE 0.08: norepinephrine 0.08 g/kg/

Eligibility

Inclusion criteria

Inclusion criteria: Women aged 18 35 years, full-term pregnant, scheduled for elective caesarean section under spinal anaesthesia, and belonging to ASA class II

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Foetal blood gas parameters obtained from umbilical artery and venous samples immediately after cord clampingTimepoint: Immediately after the delivery of the baby	—

Secondary

Measure	Time frame
Apgar scoresTimepoint: 1 & 5 minutes after delivery;Hear rate, blood pressureTimepoint: 1,2,15,30,45,60 minutes after delivery	—

Countries

India

Contacts

Public ContactDr CH RAMA KRISHNA PRASAD

AIIMS BIBINAGAR

ramakrishna.chikkala19@gmail.com09885718133

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026