Health Condition 1: L639- Alopecia areata, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Cases Clinically diagnosed patients with Alopecia Areata who did not receive any treatment in the last 3 months . Age 18 to 50 years Both males and females Controls Individuals without alopecia areata and age 18-50 years
Exclusion criteria
Exclusion criteria: Hair regrowth at the time of presentation . Patients on drugs affecting antioxidant levels like hydroxychloroquine, immunosuppresive drugs ,multivitamins or antioxidants in the last 3 months . Patients with endocrine and chronic systemic diseases like diabetes mellitus, heart failure, systemic lupus, etc. Obesity, smoking Pregnancy, and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of Nuclear factor Erythroid 2-related factor 2 (NRF-2) and Total Antioxidant Capacity (TAC) in Alopecia Areata . Timepoint: 18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of NRF-2 and TAC levels in Alopecia Areata and Healthy individuals. To assess NRF-2 and TAC levels as predictive markers of Alopecia Areata. Correlation between NRF-2 and TAC with the disease severity and the risk of development of Alopecia Areata . Clinical and Trichoscopic evaluation of Alopecia Areata. Timepoint: 18 months | — |
Countries
India
Contacts
Father Muller Medical College , Mangalore