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Comparative evaluation of effect of alkalized lidocaine versus non-alkalized lidocaine: A clinical trial

comparative evaluation anesthetic effect of alkalized lidocaine versus non-alkalized lidocaine administered in maxillary first molar with symptomatic irreversible pulpitis: randomized control trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/098308
Enrollment
141
Registered
2025-12-02
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A488- Other specified bacterial diseases

Interventions

Intervention1: 4.2 percent sodium bicarbonate: 2 percent lignocaine with 4.2% sodium bicarbonate in 1 in 10 proportion Intervention2: 8.4 percent sodium bicarbonate: 2 percent lignocaine with 8.4 perc

Sponsors

Apurva Borale
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Deep carious lesions having moderate to severe visual analogue scale score greater than 5 Aged from 16 to 45 With SIP in the mandibular molar was included

Exclusion criteria

Exclusion criteria: Recent cardiac surgery, pregnancy or lactation Premedication Necrotic teeth with associated sinus tracts Advanced periodontitis Poor oral hygiene Presence of dental fractures Large periapical radiolucency greater than 2 mm

Design outcomes

Primary

MeasureTime frame
effectiveness of Inferior Alveolar Nerve Block for pain relief in Symptomatic irreversible pulpitis using conventional and buffered lidocaineTimepoint: 2 months—

Secondary

MeasureTime frame
NILTimepoint: 00—

Countries

India

Contacts

Public ContactApurva Borale

Dr.hsrsm dental college,basamba phata ,hingoli

sunrays_gs@yahoo.co.in7972560032

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026