Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Inj. Ketamine 0.1 mg/kg: Participants in this arm will receive a single pretreatment dose of Injection Ketamine calculated at 0.1 mg/kg, diluted with Normal Saline to a total volume of
Sponsors
B. J. Medical College, Ahmedabad
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologist (ASA) Classification I, II and Elective surgery done in Major Operation Theatre Written informed consent given by patient & relative
Exclusion criteria
Exclusion criteria: American Society of Anesthesiologist (ASA) Classification III, IV and V Patients refusing to give consent Pregnant or lactating females Hypersensitivity or contraindications to the study drug Neurological, psychiatric or neuromuscular disorder Alcohol abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of Propofol injection pain. 4-point Verbal Rating Scale (VRS) by McCrirrick and Hunter Timepoint: Assessed every 5 seconds until 20 seconds during propofol injection | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative hemodynamic parameters. Metric: NIBP, HR, and SPO2. Post operative abnormal behavioral responses. Metric: Observation for hallucinations, illusions, or delirium.Timepoint: NIBP, HR, and SPO2. Recorded at baseline, after study drug, just before intubation, and at 5, 10, and 15 minutes after intubation. Observation for hallucinations, illusions, or delirium. Immediately after extubation. | — |
Countries
India
Contacts
Public ContactDr Aadil Shabirbhai Chauhan
B. J. Medical College, Ahmedabad
Outcome results
None listed