A prospective study of use of Low Dose Radiation Therapy for pain relief in patients with osteoarthritis of hands which is not controlled by routine medications

A Prospective Study of Low Dose Radiation Therapy in Osteoarthritis of Hands - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/098220

Enrollment

Registered

2025-11-28

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M190- Primary osteoarthritis of other joints

Interventions

Intervention1: Low Dose Radiation Therapy: Low Dose Radiation Therapy (300 cGy in 6 fractions over 3 weeks (50 cGy/fraction delivered twice weekly) for pain control in Osteoarthritis of Hands Control

Eligibility

Inclusion criteria

Inclusion criteria: - Diagnosed to have Osteoarthritis of the hands - Patients refractory to conventional NSAIDs to full tolerance dose - Patients needing more than two NSAIDs - Patients consenting to be a part of the study

Exclusion criteria

Exclusion criteria: - Patients with diagnosis other than Osteoarthritis - Patients who have received Radiation Therapy to the affected area earlier due to any reason - Patients not consenting to be a part of the study.

Design outcomes

Primary

Measure	Time frame
The reduction in the pain score of the patients with Osteoarthritis of the hands after low dose Radiation TherapyTimepoint: 3 & 6 months after the completion of Low Dose Radiation Therapy and then 6 monthly thereafter	—

Secondary

Measure	Time frame
The reduction in use of NSAIDs in patients with Osteoarthritis of the hands after low dose Radiation TherapyTimepoint: 3 & 6 months after the completion of Low Dose Radiation Therapy and then 6 monthly thereafter;Radiographic changes observed in the Hands in patients with Osteoarthritis after low dose Radiation TherapyTimepoint: 3 & 6 months after the completion of Low Dose Radiation Therapy and then 6 monthly thereafter	—

Measure

Time frame

The reduction in use of NSAIDs in patients with Osteoarthritis of the hands after low dose Radiation TherapyTimepoint: 3 & 6 months after the completion of Low Dose Radiation Therapy and then 6 monthly thereafter;Radiographic changes observed in the Hands in patients with Osteoarthritis after low dose Radiation TherapyTimepoint: 3 & 6 months after the completion of Low Dose Radiation Therapy and then 6 monthly thereafter

—

Countries

India

Contacts

Public ContactMayur Mayank

Medanta The Medicity

mayank.rch@gmail.com9560250562

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026