Comparing which iron treatment increases Haemoglobin more effectively and safely in treating anaemia in mothers after childbirth.

Effectiveness and Safety of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose among patients with postpartum iron deficiency anaemia: A randomized controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/11/098214

Enrollment

159

Registered

2025-11-28

Start date

Unknown

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O908- Other complications of the puerperium, not elsewhere classified

Interventions

Intervention1: Iron Sucrose: Patients in this group will receive Intravenous Iron Sucrose in multiple divided doses as calculated by Ganzoni formula. Intervention2: Ferric Carboxymaltose: Patients in

Eligibility

Inclusion criteria

Inclusion criteria: 1. Females aged between 18-45 years. 2. Haemoglobin is more than or equal to 7 g/dL and less than 11 g/dL in the first 48 hours after delivery. 3. Patient is willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with haemolytic anaemia, aplastic anaemia, sickle cell anaemia and macrocytic anaemia. 2. Previous history of allergic reaction to Ferric Carboxymaltose or Iron Sucrose. 3. Patients with history of chronic heavy metal toxicity. 4. Patients suffering from chronic kidney disease.

Design outcomes

Primary

Measure	Time frame
To compare the effectiveness of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose on change in Haemoglobin in postpartum iron deficiency anaemia from baseline to 6 weeks.Timepoint: Baseline, 6 weeks	—

Secondary

Measure	Time frame
To compare the effectiveness of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose on change in Ferritin in postpartum iron deficiency anaemia from baseline to 6 weeks and 10 weeks.Timepoint: Baseline, 6th week, 10th week;To compare the effectiveness of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose on change in Haemoglobin in postpartum iron deficiency anaemia after 10 weeks postpartum.Timepoint: Baseline, 10th week;To evaluate the change in EPDS Score of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose in postpartum iron deficiency anaemia from baseline to 6 weeks and 10 weeks.Timepoint: Baseline, 6th week, 10th week;To evaluate the safety and compliance of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose in postpartum iron deficiency anaemia at baseline, 2 weeks, 6 weeks, and 10 weeks.Timepoint: Baseline, 2nd week, 6th week, 10th week;To compare the cost effectiveness analysis of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose in postpartum iron deficiency anaemia after 10 weeks.Timepoint: Baseline, 10th week	—

Measure

Time frame

To compare the effectiveness of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose on change in Ferritin in postpartum iron deficiency anaemia from baseline to 6 weeks and 10 weeks.Timepoint: Baseline, 6th week, 10th week;To compare the effectiveness of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose on change in Haemoglobin in postpartum iron deficiency anaemia after 10 weeks postpartum.Timepoint: Baseline, 10th week;To evaluate the change in EPDS Score of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose in postpartum iron deficiency anaemia from baseline to 6 weeks and 10 weeks.Timepoint: Baseline, 6th week, 10th week;To evaluate the safety and compliance of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose in postpartum iron deficiency anaemia at baseline, 2 weeks, 6 weeks, and 10 weeks.Timepoint: Baseline, 2nd week, 6th week, 10th week;To compare the cost effectiveness analysis of Ferrous Ascorbate vs Iron Sucrose vs Ferric Carboxymaltose in postpartum iron deficiency anaemia after 10 weeks.Timepoint: Baseline, 10th week

—

Countries

India

Contacts

Public ContactDr Vaibhav Mundra

All India Institute of Medical Sciences, Jodhpur

kumart@aiimsjodhpur.edu.in9599634860

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026