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EFFECT OF ESMOLOL VS DEXMEDETOMIDINE ON EXTUBATION QUALITY SCORE DURING TRACHEAL EXTUBATION IN ADULT PATIENTS UNDERGOING GENERAL ANESTHESIA

EFFECT OF ESMOLOL VS DEXMEDETOMIDINE ON EXTUBATION QUALITY SCORE DURING TRACHEAL EXTUBATION IN ADULT PATIENTS UNDERGOING GENERAL ANESTHESIA - A COMPARATIVE RANDOMIZED STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/11/098107
Enrollment
52
Registered
2025-11-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Intravenous Esmolol 1mg/kg: Intravenous Esmolol 1mg/kg 3 min given before skin suture completion Intervention2: Nil: Nil Control Intervention1: Intravenous Dexmedetomidine 0.5mcg/kg: In

Sponsors

Smt.Bhikiben Kanjibhai Shah Medical Institute and Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to sign informed consent Male or Female patients between 18 to 65 years of age Patients belonging to American Society of Anaesthesiologists (ASA) physical status I & II Patients posted for elective surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
This prospective and comparative study will help us to compare the efficacy between esmolol and dexmedetomidine in attenuating hemodynamic responses to endotracheal extubation in patients undergoing surgeries under general anaesthesia by having better outcome in hemodynamicsTimepoint: This prospective and comparative study will help us to compare the efficacy between esmolol and dexmedetomidine in attenuating hemodynamic responses to endotracheal extubation in patients undergoing surgeries under general anaesthesia by having better outcome in hemodynamics

Secondary

MeasureTime frame
study will help us to compare the efficacy between esmolol and dexmedetomidine in attenuating hemodynamic responses to endotracheal extubation in patients undergoing surgeries under general anaesthesia by having better outcome in hemodynamics.Timepoint: Pre operative Before drug administration After test drug administration 1min 2min 3min 4min 5min 6min 7min 8min 9min 10min 11min 12min 13min 14min 15min 16min 17min 18min 19min 20min After extubation (in minutes) 1min 2min 3min 4min 5min 15min 30min 45min 60min 75min 90min 105min 120min

Countries

India

Contacts

Public ContactDr Dinesh Chauhan

Smt.Bhikiben Kanjibhai Shah Medical Institute and Research Centre

drdinesh77@gmail.com9099014672

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026