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Comparison of iPACK block versus local infiltration analgesia for total knee arthroplasty

Comparison of the role of the iPACK Interspace between the Popliteal Artery and the Capsule of the Posterior Knee block versus local infiltration analgesia as part of a multimodal regimen for total knee arthroplasty - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/098101
Enrollment
78
Registered
2025-11-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: M238- Other internal derangements of knee

Interventions

Intervention1: iPACK (interspace between popliteal artery and the capsule of the posterior knee: 20 ml of 0.2% Ropivacaine administered under ultrasound guidance as a single intervention before the st

Sponsors

Dr Aparna Shantesh Kaushik
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2 undergoing elective unilateral total knee replacement under spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1. Patient refusal to participate 2. Patient refusal for spinal anaesthesia 3.any contraindications for spinal anaesthesia 4. Coagulopathy or bleeding disorders 5.infection or injury at the site of block administration 6.history of allergy to any local anaesthetic or adjuvants 7. Patients with peripheral neuropathy 8. Patients classified as ASA grade 3 and 4

Design outcomes

Primary

MeasureTime frame
1.VAS Scores 2. Duration of analgesia 3. Requirement of rescue analgesiaTimepoint: 8 hour interval upto 48 hours post operatively

Secondary

MeasureTime frame
Mobilization Post-operative haemodynamics Any adverse effectsTimepoint: 8 hour interval upto 48 hours post operatively

Countries

India

Contacts

Public ContactDr Farha Tarig Sed Ahmed

Wockhardt Hospitals

farhatarig@gmail.com9372323813

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026