Study to compare the Effect of Dexamethasone Versus Dexmedetomidine as an additive to Ropivacaine in Transversus Abdominis Plane Block for Postoperative Analgesia in Patients undergoing Caesarean Section under Spinal Anaesthesia

Efficacy and Safety of Dexamethasone Versus Dexmedetomidine as an adjuvant to Ropivacine in Transversus Abdominis Plane Block for Postoperative Analgesia in Patients undergoing Caesarean Section undergoing Spinal Anaesthesia - A Comparative Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/098066

Enrollment

Registered

2025-11-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Transversus Abdominis Plane block using Inj Ropivacaine with Inj Dexamethasone: To administer Transversus Abdominis Plane block using Inj Ropivacaine 0.2% 40ml with Inj Dexamethasone 8m

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing lower segment caeserian section procedure under spinal anaesthesia will be included in the study. Weight 55-90 kg and Patients graded ASA 1 and ASA 2.

Exclusion criteria

Exclusion criteria: Patients with pre-existing bradycardia and conducting blocks, on beta adrenergic blockers, diabetes mellitus, morbid obesity, allergy to study drugs, patients whose plan of anaesthesia gets converted to general anaesthesia.

Design outcomes

Primary

Measure	Time frame
Duration of postoperative analgesia, Total VAS score in 24 hours, Number of rescue analgesia requested in the first 24 hoursTimepoint: To study and compare Duration of postoperative analgesia, Total VAS score in 24 hours, Number of rescue analgesia requested in the first 24 hours among the two study groups.	—

Secondary

Measure	Time frame
To study & compare hemodynamic parameters, Ramsay sedation score, side effects like bradycardia, hypotension, nausea & vomitingTimepoint: To study & compare hemodynamic parameters, Ramsay sedation score, side effects like bradycardia, hypotension, nausea & vomiting over time periods - 30 minutes, 1 hour, 2 hours, 4 hours, 6 hours, 8 hours, 12 hours, 24 hours.	—

Countries

India

Contacts

Public ContactDr Pradnya Joshi

MGM Medical College and Hospital

joshispradnya@gmail.com9823752665

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026