Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Exploring the therapeutic effects of repetitive transcranial magnetic stimulation on quality of sleep observed by polysomnography, brain-derived neurotrophic factors and melatonin -in p
Sponsors
Council of Science & Technology U.P.
Eligibility
Inclusion criteria
Inclusion criteria: Post stroke patient aged 18 to 65 years who has a sleep disorder evidenced by a PSQI score
Exclusion criteria
Exclusion criteria: Patients with impaired cognitive function History of drug intake that can affect the sleep cycle Altered sensorium or impaired consciousness Suffering from post-stroke depression as evidenced by the Beck Depression Inventory score Previous history of sleep disorder before stroke
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Improvement in PSQI scores post-rTMS and sustained benefits at three months. 2.Enhancement in sleep architecture parameters (TST, SE, SL, N3, and REM). 3.Increase in serum BDNF and melatonin levels post-intervention, reflecting improved neuroplasticity and circadian regulation. Timepoint: 1 month intervention and 3 months outcome | — |
Secondary
| Measure | Time frame |
|---|---|
| The effect of rTMS on PSG, 3 months after intervention. 3. The effect of rTMS on serum BDNF and melatonin level after intervention and at 3 months. Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactANKIT KUMAR DIXIT
AIIMS Raebareli
Outcome results
None listed