Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Reboot surgery: This approach involves extensive removal of the diseased
mucosa to address the underlying inflammation that drives polyp
recurrence. The procedure can vary in extent:
o
Sponsors
JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: 1. All adult patients of either gender and age 18 years- 60 years with a confirmed diagnosis of CRSwNP (including extensive polyposis) 2. Persistent symptoms despite a minimum of 12 weeks of maximal medical therapy, including intranasal corticosteroids. 3. Patients willing to provide informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of previous sinus surgery within the last five years. 2. Presence of severe co-morbid conditions such as uncontrolled asthma or immunodeficiency. 3. Patients using biologic therapy within the last 12 months. 4. History of sinonasal malignancy or conditions other than CRSwNP causing nasal obstruction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the postoperative sinonasal outcomes, measured by SNOT-22 scores, between patients undergoing Re-boot surgery and those undergoing FESS (non Re-boot) (traditional mucosa-sparing) surgery for chronic rhinosinusitis with nasal polyps (CRSwNP).Timepoint: Preop and 3 months postop | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To assess the impact of the surgeries on olfactory function (measured by subjective smell scores). 2. To evaluate polyp recurrence rates at 3 months post-surgery.Timepoint: Pre-op and 3 months postop | — |
Countries
India
Contacts
Public ContactDr Neelam Chittiappa
Jawaharlal Institute of Postgraduate Medical Education and Research
Outcome results
None listed