A STUDY ON EFFICACY, SAFETY, AND TOLERABILITY OF SALICYLIC ACID PEEL WITH ORAL ITRACONAZOLE VS ORAL ITRACONAZOLE IN THE MANAGEMENT OF TINEA CORPORIS INFECTION

A PROSPECTIVE, RANDOMIZED STUDY ON EFFICACY, SAFETY, AND TOLERABILITY OF 30% SALICYLIC ACID PEEL WITH ORAL ITRACONAZOLE VS ORAL ITRACONAZOLE IN THE MANAGEMENT OF TINEA CORPORIS INFECTION - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/097925

Enrollment

Registered

2025-11-24

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B354- Tinea corporis

Interventions

Intervention1: 30% salicylic acid peel with oral itraconazole: 30% salicylic acid peel applied locally once a week along with oral itraconazole 100 mg tablet given two times a day for 4 weeks. Control

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are clinically and mycologically positive KOH mount diagnosed case of Tinea corporis. Both sexes men and women Age above 18 years to 60 years Patients with less than 20 percent of body surface area involvement. Patient who will give consent

Exclusion criteria

Exclusion criteria: Patients with negative KOH mount and patients who will not give consent. Patients having patches in more than 20 percent BSA Age less than 18 years, Age more than 60 years,pregnancy and lactation Patients with erosions,open wound,secondary infection,maceration at patch area Patients with intertriginous involvement Patients with anemia,liver diseases,kidney diseases, GI diseases Patients with malignancy and lymphoproliferative disorders Patients on potent immunosuppresants,biological DMARDS,organ transplant history Patients with derranged liver and kidney profile Patients using topical or oral antifungals within the preceding 2 weeks Patients known allergic to salicylic acid

Design outcomes

Primary

Measure	Time frame
To assess the clinical efficacy of 30% salicylic acid peel with oral Itraconazole vs oral Itraconazole in management of tinea corporis infectionTimepoint: To assess the clinical efficacy of 30% salicylic acid peel with oral Itraconazole vs oral Itraconazole in management of tinea corporis infection	—

Secondary

Measure	Time frame
To study the safety and tolerability of 30% salicylic acid peel with oral Itraconazole vs oral Itraconazole in the management of tinea corporis infectionTimepoint: 3 months	—

Countries

India

Contacts

Public ContactDr Visheshkumar Pralhadrao Mohature

Shri Bhausaheb Hire Government Medical College

avisajgane@gmail.com8879376867

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026