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Evaluating the effect of low dose of the drug Ketamine in reducing the pain after child is delivered in a caesarean section surgery

Evaluation of efficacy of low dose ketamine in relieving intraoperative post child birth pain in lower segment caesarean section: a prospective, randomised, double-blind case control study - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097884
Enrollment
80
Registered
2025-11-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: the intra operative pain relief comparison: To determine the intraoperative pain relief, patient is given 0.5mg/kg Ketamine IV in comparison to patient receiving similar volume of NS, f

Sponsors

Maharana Bhupal Government Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Parturients with Singleton pregnancy (37-42 weeks) Elective LSCS ASA Grade II

Exclusion criteria

Exclusion criteria: Patient Refusal Non cooperative Parturients Patients with medical comorbidities like, cardiac diseases such as inadequate left ventricular ejection fraction (Ejection Fraction less than 45%), valvular or ischaemic heart disease, uncontrolled hypertension, heart blocks, arrhythmia, cardiac failure, uncontrolled diabetes mellitus, hepatic, renal, endocrine, haematological, autoimmune, psychiatric, neurological diseases, neuromuscular diseases, bronchial asthma, chronic obstructive pulmonary disease. Allergy to study drug - Ketamine Patients who participated in another study within 30 days

Design outcomes

Primary

MeasureTime frame
To Evaluate the intra operative pain relief achieved for the patient on giving 0.5 mg/kg of Ketamine intravenously following child deliveryTimepoint: After childbirth at 0,2,5,10,15,20,30 mins intraoperatively and at End of surgery

Secondary

MeasureTime frame
To evaluate the post operative analgesic effect of low dose ketamineTimepoint: At 2,6 ,12 and 24 hours post operatively.;To look for any adverse effects/complications associated with administration of ketamineTimepoint:

Countries

India

Contacts

Public ContactDr Arjun P Raj

RNT Medical College

htungaria@gmail.com9829370866

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026