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A Comparison of Fentanyl and Diclofenac Skin Patches for Pain Relief After Abdominal Surgery

Comparative Evaluation Of Fentanyl Transdermal Patch With Diclofenac Transdermal Patch For Post Operative Pain Relief In Patients Undergoing Laprotomy Surgeries - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097861
Enrollment
66
Registered
2025-11-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C540- Malignant neoplasm of isthmus uteri Health Condition 2: N858- Other specified noninflammatory disorders of uterus

Interventions

Intervention1: FENTANYL TRANSDERMAL PATCH: All patients satisfying inclusion criteria will undergo detailed pre-anesthetic evaluation including history, complete physical examination, and necessary in

Sponsors

Dr Atul Rajput
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 18 to 65 yrs ASA Grade I & II Undergoing laparotomy surgeries

Exclusion criteria

Exclusion criteria: known allergy to study drugs patients with local skin conditions preventing patch application Known opioid dependents and chronic opioid use pregnant and lactating mothers

Design outcomes

Primary

MeasureTime frame
Degree of postoperative pain relief by using transdermal fentanyl with transdermal diclofenac patch measured by Visual analog scale (VAS) score.Timepoint: Visual analogue scale (VAS) for pain will be assessed post operatively at 1 hr, 2 hr, 4 hr, 8 hr, 24 hr and 48 hrs after surgery

Secondary

MeasureTime frame
Time for first rescue analgesia Total dose of rescue analgesia in first 24 hours To assess the Ramsay sedation score (RSS)Timepoint: Time of first request for rescue analgesia and number of doses required during first 24 hours and 48 hours will be noted. Ramsay sedation scoring will be assessed at 1hr, 2 hr., 4 hr., 8hr and 24 hr. and 48 hrs. after surgery.

Countries

India

Contacts

Public ContactDr Madhu Bala

Vardhaman Mahavir Medical College And Safdurjung Hospital

madhubsayal@gmail.com9818997757

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026