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Linking What We See on the Skin to What Happens Under the Microscope in Lichen Planus

Clinical , Histopathological and Immunohistochemical Correlation of Severity in Lichen Planus - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097855
Enrollment
43
Registered
2025-11-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L433- Subacute (active) lichen planus

Interventions

Intervention1: Skin biopsy: An incisional biopsy will be performed under local anaesthesia and tissue samples will be formalin fixed, paraffin-embedded, and sectioned for hematoxylin and eosin and i

Sponsors

FATHER MULLER RESEARCH CENTRE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of age 18years and above. 2. Treatment naive cases . patients who received topical treatment for 2 weeks prior or patients on systemic therapy for 4 weeks prior 3. Patients of all gender

Exclusion criteria

Exclusion criteria: 1 Immunologically compromised patients and Pregnant women

Design outcomes

Primary

MeasureTime frame
Histopathological scoring of Lichen planus .Timepoint: Clinical severity in histopathology—

Secondary

MeasureTime frame
To analyze the expression of CD4 , CD8, CD1a and CD 34 .Timepoint: To assess correlation among clinical severity , histopathology and immunohistochemical findings in Lichen planus—

Countries

India

Contacts

Public ContactDr Nisha marla

Father mullermedical college

rameshderma@gmail.com9845084224

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026