Testing if Zinc Oxide and Sodium Hyaluronate coated Wire when used during orthodontic treatment will provide better treatment outcomes compared to those with uncoated wires.

Development and Evaluation of Clinical efficacy of Novel Zinc oxide and Sodium Hyaluronate coated Stainless steel orthodontic archwire -Randomised control study.

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/11/097853

Enrollment

Registered

2025-11-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: ZnO-SH coated 0.019 x 0.025 orthodontic arch wire: Split-mouth study using 0.019 0.025-inch stainless steel orthodontic archwires where one half of each wire is coated with zinc oxide a

Eligibility

Inclusion criteria

Inclusion criteria: All 4 or upper 4 extraction cases ( upper 1 st premolar extraction cases)after end of levelling and aligning.

Exclusion criteria

Exclusion criteria: Patient with systemic illness.

Design outcomes

Primary

Measure	Time frame
1. Rate of tooth movement 2. Bacterial adhesion Timepoint: 1. Rate of tooth movement- 3 months 2. Bacterial adhesion-1 month	—

Secondary

Measure	Time frame
1. coating wear and surface roughness of archwire 2.Notching of the archwire after retraction.Timepoint: 1. coating wear and surface roughness of the archwire - 1month 2.Notching of the archwire after retraction-3-6months	—

Countries

India

Contacts

Public ContactNajiya VP

Saveetha Dental College, Chennai

shanthakkss@gmail.com9444443640

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026