Health Condition 1: C480- Malignant neoplasm of retroperitoneum
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or above 2. Histologically confirmed liposarcomas and leiomyosarcomas presenting initially to this institutewithout previous treatment- except for NACT. 3. Resectable tumors
Exclusion criteria
Exclusion criteria: 1. Recurrent cases 2. Preoperative RT
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To evaluate difference inoverall survival(OS) in patients undergoing upfront surgery and NACT followed by surgery in resectable retroperitoneal liposarcomas and leiomyosarcomasTimepoint: 3 monthly for first 2 years after surgery then 6 monthly for next 3 years | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To study recurrence ratesin patients undergoing upfront surgery vs NACT followed by surgery in resectable retroperitoneal liposarcomas and leiomyosarcomasTimepoint: 3 monthly for first 2 years after surgery then 6 monthly for next 3 years;2. Complete resection rates in the two groupsTimepoint: 3 monthly for first 2 years after surgery then 6 monthly for next 3 years;3. Tumour downstaging rates in with NACTTimepoint: 3 monthly for first 2 years after surgery then 6 monthly for next 3 years;3. Pathological response ratem recurrence patterns and post operative morbidity and mortality in the two groupsTimepoint: 3 monthly for first 2 years after surgery then 6 monthly for next 3 years | — |
Countries
India
Contacts
Public ContactDr Shraddha Padkar
Tata memorial Hospital, Mumbai
Outcome results
None listed