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Comparison of two commonly used antiseptic solutions (alcohol-based vs. povidone-iodine) to prevent wound infections after surgery.

A Prospective, Randomized Controlled Trial Comparing 2 Propanol plus Benzalkonium Chloride versus Povidone Iodine for the Prevention of Surgical Site Infections

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097794
Enrollment
434
Registered
2025-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: B998- Other infectious disease

Interventions

Intervention1: Arm A (Experimental): 2-propanol 70% + Benzalkonium chloride 0.13%.: Arm A (Experimental): 2-propanol 70% + Benzalkonium chloride 0.13%., applied twice pre-op with drying time of 2 minu

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria (18 years, clean/clean-contaminated elective surgeries, ASA I III)

Exclusion criteria

Exclusion criteria: Exclusion criteria (allergy, emergency surgery, immunocompromised, pregnancy/lactation, neonates)

Design outcomes

Secondary

MeasureTime frame
Time to onset of SSITimepoint: From day of surgery to postoperative day 30.;Classification of SSITimepoint: Time Point: Day 7, Day 14, Day 30.;Local skin reactionsTimepoint: Day 0, Day 1, Day 7, Day 14.;Adverse eventsTimepoint: Day 0 to Day 30.;Cost-effectivenessTimepoint: At end of follow-up (Day 30).—

Primary

MeasureTime frame
Incidence of SSI within 30 days post-surgery, defined by CDC criteria.Timepoint: Incidence of surgical site infection at postoperative day 7, day 14, day 30.—

Countries

India

Contacts

Public ContactDr Sameer Uttamrao Khasbage

AIIMS, RAIPUR

samkhasbage@gmail.com9579502670

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026