How Surface design affects germ growth on Clear Aligners : A comparison between new Direct printed and regular thermoformed aligners.

Comparative evaluation of Surface properties and Biofilm growth on 3D printed and thermoformed Clear aligners An In Vivo prospective study - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/097752

Enrollment

Registered

2025-11-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K038- Other specified diseases of hard tissues of teeth

Interventions

Intervention1: 3D printed: wearing the 3D printed aligners for 2 weeks Control Intervention1: Thermoformed aligner: wearing the thermoformed aligner for 2 weeks

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 18 years to 40 years with healthy permanent dentition, healthy periodontium, and excellent oral hygiene. Patients that require mild correction of malocclusion within the scope of Clear aligner treatment.

Exclusion criteria

Exclusion criteria: Patients with Craniomandibular disorders, and /or any systemic conditions Patients with Pathological conditions such as Bruxism and clenching Patients who smoke or consume tobacco Patients with poor oral hygiene or poor perceived compliance Patients who are pregnant or are breastfeeding Immunocompromised patients.

Design outcomes

Primary

Measure	Time frame
Surface properties and Biofilm growth.Timepoint: Baseline and After 2 weeks of intra oral use	—

Secondary

Measure	Time frame
nilTimepoint: none	—

Countries

India

Contacts

Public ContactDr Robin Mathew Neerumtharappel

Terna Dental College and Hospital

robin.23pden102@student.nitte.edu.in9930851339

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026