Comparing iv magnesium sulphate vs iv esmolol to hemodynamic changes during extubation after neurosurgeries

Comparitive study of iv magnesium sulphate vs iv esmolol in attenuation of hemodynamic response during extubation after general anaesthesia in elective neurosurgeries - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/097703

Enrollment

Registered

2025-11-19

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M489- Spondylopathy, unspecified

Interventions

Intervention1: Comparitive study of iv magnesium sulphate vs iv esmolol in attenuation of hemodynamic response during extubation after general anaesthesia in elective neurosurgeries: Patients undergoi

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients posted for elective neurosurgery under general anaesthesia. 2.Age 18years to 60 years.3.American Society of Anaesthesia physical status I and II.4.Patients who are willing to give consent for the study.

Exclusion criteria

Exclusion criteria: Patient allergic to the study drug.

Design outcomes

Primary

Measure	Time frame
To compare effects of IV Magnesium Sulphate vs IV Esmolol in attenuation of hemodynamic response during extubation after general anaesthesia in elective neurosurgeries.Timepoint: To compare effects of IV Magnesium Sulphate vs IV Esmolol in attenuation of hemodynamic response during extubation after general anaesthesia in elective neurosurgeries over 30 minutes	—

Secondary

Measure	Time frame
To assess the degree of sedation post Extubation.Timepoint: 30minutes	—

Countries

India

Contacts

Public ContactDr Prabha P

Sapthagiri institute of medical sciences and research institute

prabhap1510@gmail.com9448055973

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026