Health Condition 1: A09- Infectious gastroenteritis and colitis, unspecified
Conditions
Interventions
Intervention1: Addition of probiotic to the standard therapy (ORS plus Zinc): Bacillus clausii suspension of 5ml (2 billion spores)once a day to group A will be given for 5 days or earlier if resolved
Sponsors
Department of Paediatrics
Eligibility
Inclusion criteria
Inclusion criteria: 1) Children aged 6 months to 59 months 2)Onset of acute diarrhea in the last 48 hours (Defined as 3 or more stools per day)
Exclusion criteria
Exclusion criteria: 1)Chronic diarrhea(Diarrhea lasting more than 14 days) 2)Severe acute malnutrition 3)Known immunodeficiency syndromes (eg HIV, primary immunodeficiency disorders) 4)Dysentry(Loose stools associated with blood) 5)Severe comorbid conditions(Congenital heart disease,chronic kidney disease) 6)Recent antibiotic use in the last 7 days 7)Known hypersensitivity to probiotics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of diarrhea from the first dose Of intervention to the last unformed stoolTimepoint: baseline,24 hours, 48 hours,72 hours, 96 hours, 120 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Severity score using Modified vesikari scale 2)Frequency of stools per day 3)Need of hospitalization 4) Duration of hospital stay Timepoint: 1)Modified vesikari scale at baseline,24 hours, 48 hours, 72 hours, 96 hours, 120 hours 2)Frequqncy of stools at baseline ,24 hours, 48 hours, 72 hours, 96 hours, 120 hours 3) Need of hospitalization at baseline, 24 hours, 48 hours, 72 hours, 96 hours, 120 hours 4)Duration of hospital stay for 1-5 days | — |
Countries
India
Contacts
Public ContactDR SAMEER BHATIA
Noida International Institute of Medical Sciences
Outcome results
None listed