Health Condition 1: K739- Chronic hepatitis, unspecified
Conditions
Interventions
None listed
Sponsors
AKSHITA
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients between the age group of 18 to 65 years. 2. Patients irrespective of sex, religion and occupation. 3. Patients with ALT levels ranging from the upper limit of normal to twice the upper limit of normal 41 to 82 will be selected. 4. Patients with low level of HBV DNA will be selected less then 20,000IU/ml for HBeAg positive patients and less then 2000IU/ml for HBeAg negative patients. 5. Patients with symptoms and signs of chronic hepatitis B and diagnosed chronic hepatitis B infection will be selected.
Exclusion criteria
Exclusion criteria: 1. Concurrent infection with hepatitis C, D or other hepatic viral infection , autoimmune hepatitis or alcoholic hepatitis. 2. Significant comorbidities such as liver cirrhosis, renal failure or cardiovascular diseases. 3. Pregnant or breastfeeding women. 4. Decompensated liver disease. 5. Patient suffering from Ascites, hepatic encephalopathy, variceal bleeding. 6. Hepatocellular carcinoma. 7. Patients who have previously taken Interferons or antiviral agents, Corticosteroids,immunosuppressive drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in HBV DNA levels with ALT normalization after treatment.Timepoint: Evaluation of reduction in viral load (HBV DNA) and ALT levels will be assessed at follow-up visits scheduled on the 30th, 60th, and 90th day after initiation of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of improvement in clinical symptoms, liver enzyme normalization trend, and overall quality of life; along with assessment of safety and tolerability of the intervention.Timepoint: 18 months | — |
Countries
India
Contacts
Public ContactAKSHITA
Quadra Institute Of Ayurveda And Hospital
Outcome results
None listed