A study to compare the preparation, analysis and antidepressant effect of brahmi ghruta and brahmi sugar granules in the management of premenstrual syndrome (PMS).

A Comparative Pharmaceutico Analytical Study Of Brahmi Ghruta And Brahmi Sugar Granules With Its Comparative Anti Depressant Action In Management Of Premenstrual Syndrome. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/097670

Enrollment

Registered

2025-11-18

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F321- Major depressive disorder, singleepisode, moderate

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients having sign symptoms of premenstrual depression,symptoms according DSM-4 criteria.

Exclusion criteria

Exclusion criteria: 1)Known history pf head injury,mental retardation,or any other psychiatric illness. 2)Females on hormomal therepy, known endocrinal, gynecological disorder or physical illness. 3Patients less than 20 years of age and above 40 years of age.

Design outcomes

Primary

Measure	Time frame
Clinical Efficacy (Antidepressant effect) Change in depression score using Hamilton Depression Rating Scale (HDRS-17) before and after intervention. To evaluate and compare the reduction in depressive symptoms associated with premenstrual syndrome in both groups (Brahmi Ghruta and Brahmi Sugar Granules). Timepoint: Baseline and post-treatment of 28 days period.	—

Secondary

Measure	Time frame
1.Improvement in asscociated symptoms of PMS. Change in PMS-related somatic and emotional symptoms(eg.irritability, fatigue,sleep distrubence, bloating,headache) Assessment Tool- HDRS 17Timepoint: Baseline and post-treatment of 28 days period. ;2.Pharmaceutical and Analytical Comparision. Organoleptic characteristics,physiochemical parameters and HPTLC profiling of Brahmi Ghruta and Brahmi Sugar Granules.Timepoint: Preclinical analytical phase(before administration)	—

Measure

Time frame

1.Improvement in asscociated symptoms of PMS. Change in PMS-related somatic and emotional symptoms(eg.irritability, fatigue,sleep distrubence, bloating,headache) Assessment Tool- HDRS 17Timepoint: Baseline and post-treatment of 28 days period. ;2.Pharmaceutical and Analytical Comparision. Organoleptic characteristics,physiochemical parameters and HPTLC profiling of Brahmi Ghruta and Brahmi Sugar Granules.Timepoint: Preclinical analytical phase(before administration)

—

Countries

India

Contacts

Public ContactDr Gaurav Dongare

Ashwin Rural Ayurved College And Hospital, Manchi Hill.

vdgauravdongare.gd@gmail.com9588654040

Outcome results