Health Condition 1: G610- Guillain-Barre syndrome Health Condition 2: G700- Myasthenia gravis
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Sponsors
NIMHANS
Eligibility
Inclusion criteria
Inclusion criteria: Patients admitted to ICU with Guillain Barre Syndrome or Myasthenia Gravis who are conscious and oriented.
Exclusion criteria
Exclusion criteria: Patients who are sedated and ventilated. Patients with a known history of hearing deficits, seizure disorder, intellectual disability, and psychiatric illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the prevalence of sleep deprivation (total sleep time less than 7 hours with Arousal index more than 20 per hour). To determine patterns of sleep disturbances such as changes in sleep stages (N1, N2, N3, REM), wakefulness after sleep onset (WASO), sleep efficiency, sleep onset latency, day time sleep, total sleep (consist of any sleep stages) in 16-24h. Timepoint: Day 2 of ICU admission for 16-24 hours Day 5-7 of ICU admission for 16-24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess subjective sleep quality using Richard Campbell Sleep Questionnaire (RCSQ). To compare objective polysomnography (PSG) findings with subjective questionnaire responses. To assess the temporal change in the sleep patterns over time. Association of sleep patterns with pain (VAS scores) & ICU delirium (CAM ICU scores). To understand micro-sleep architecture patterns (i.e., EEG spectral patterns, spindle parameters, slow wave parameters, slow-wave-spindle coupling & REM pattern analysis. Timepoint: Day 1-7 of ICU admission | — |
Countries
India
Contacts
Public ContactRohini M Surve
NIMHANS
Outcome results
None listed