None listed
Conditions
Interventions
Intervention1: Topical Pirfenidone gel: Drug delivery via carbon dioxide laser then application of topical Pirfenidone gel which has antifibrotic and anti inflammatory properties
twice daily , local
Sponsors
Sanjeevani Gupta
Eligibility
Inclusion criteria
Inclusion criteria: Individuals aged more than 18 years Patients with clinically diagnosed keloid scars confirmed by history and examination Willingness to avoid other scar treatments during the study period Ability to give written informed consent
Exclusion criteria
Exclusion criteria: Active infection or ulceration over or around the keloid site History of keloid treatment within the past 3 months eg steroid injections, laser, cryotherapy Patients on systemic steroids, immunosuppressants, or anticoagulants Pregnant or lactating women Known hypersensitivity or allergy to pirfenidone or laser procedures. History of hypertrophic scars or other dermatological conditions mimicking keloids. Patient with systemic diseases affecting wound healing uncontrolled diabetes, autoimmune disease Patients with unrealistic expectations HIV, Hepatitis C, Hepatitis B positive patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in keloid size , symptomatic relief and scar appearance Timepoint: assessment after 4 weeks , 8 weeks . 12 weeks , 16 weeks , 20 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactSanjeevani Gupta
Jawaharlal Nehru Medical College , Datta Meghe Institute Of Higher Education And Research ,
Outcome results
None listed