Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Ketamine 0.5mg/kg/h: Study participants will be randomized into two groups.Intervention group will receive ketamine infusion 0.5mg/kg/h approximately 5 mins before the creation of pne
Sponsors
Kiki Maria Marak
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients of age group 18-60 years 2.Patients of either sex 3.Patient with American society of Anaesthesiologists(ASA) Grade I or II 4.Patients undergoing laparoscopic cholecystectomy
Exclusion criteria
Exclusion criteria: 1.Patients with heart rate less than 60 per minute or on beta blockers 2.Psychiatric disorders 3.History of obstructive sleep apnea 4.Severely deranged hepatic and renal function 5.Lack of consent 6.Known allergy to study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare the recovery profile of ketamine and fentanyl infusion during balanced anaesthesiaTimepoint: Ramsay sedation score will be recorded at endotracheal extubation and after 15mins of shifting to post operative care unit | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Intra operative hemodynamic stability 2.time of first request of postoperative analgesia 3.Postoperative nausea and vomitingTimepoint: 1.Hemodynamic parameters(heart rate,blood pressure,mean arterial pressure) will be recorded every 5 mins throughout the procedure 2.Time of first request for rescue analgesia at Post anaesthetic care unit or at ward will be noted 3.Any episode of nausea or vomiting during stay at post anaesthesia care unit will be noted | — |
Countries
India
Contacts
Public ContactL Pradipkumar Singh
Regional Institute of Medical Sciences Imphal
Outcome results
None listed