Health Condition 1: C718- Malignant neoplasm of overlappingsites of brain
Conditions
Interventions
Intervention1: Intra-operative ultrasound: Intra-operative (real-time) imaging done once in addition to pre-operative imaging, to check extent of resection
Control Intervention1: Pre-operative imaging
Sponsors
AIIMS, New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with radiologically diagnosed glioma 2. Patients planned for radical surgical resection 3. Patients giving consent for study
Exclusion criteria
Exclusion criteria: 1. Patients unfit for surgery or general anesthesia 2. Previous cranial surgery affecting IOUS interpretation 3. Patients in whom radical resection is not feasible or is not being attempted i.e diffuse lesions, multifocal lesions, patients planned for biopsy 4. Patients planned for awake surgery (as blinding cannot be done)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the effectiveness of intra-op ultrasonography in guiding glioma resections and its impact on extent of resectionTimepoint: 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate neirological outcomes and complications post-operativelyTimepoint: 2yrs;Subgrouping based on grade of tumour (low grade vs high grade)Timepoint: 2 years;To compare overall survival rates and progression-free survival ratesTimepoint: 2 years;To assess quality of life post-operativelyTimepoint: 2 years | — |
Countries
India
Contacts
Public ContactPreethi Koppuravuri
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed