Arthritis of Knee that develops after knee injury

Effectiveness of Individualised Homoeopathic Medicine using Kent Repertory in Post-Traumatic Osteoarthritis of Knee - An Open-Label Interventional Prospective Clinical Study - PTOA

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/097509

Enrollment

Registered

2025-11-17

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue Health Condition 2: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Individualised Homoeopathic Medicine: Indicated individualised homoeopathic medicine will be prescribed after repertorisation of the case using rubric within Kent repertory. Dose and fr

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosed Osteoarthritis of the knee as per American College of Rheumatology (ACR) clinical/radiological classification criteria self-reported history of trauma (within 1-20 years) over the knee joint, knee pain, morning stiffness less than 30mins., crepitus on knee motion, osteophytes on knee x-ray. 2. Participants of all socio-economic status, all religions. 3. Ability to read/understand Bengali/Hindi/English. 4. Participants giving written consent to participate in this study. 5. Participants who agree to comply with the protocol. 6. Participants who agree to undergo laboratory investigation whenever required. 8. Participants willing to take part in the study and for regular follow-ups.

Exclusion criteria

Exclusion criteria: 1. Severe degeneration of knee joint with marked joint narrowing, evidenced by imaging or other evidences and requiring surgical intervention 2. Joint disorders other than osteoarthritis (e.g., inflammatory joint disease, increased serum uric acid level, or positive rheumatoid factor, or any clinical evidence of psoriatic arthritis, varus or valgus deformity of knee (greater than 12degree), joint prosthesis of lower limb) 3. Transplanted knees 4. Participants with unstable mental or psychiatric illness or under the control of some corticosteroids or other medications 5. Pregnant or lactating women 6. Immune-compromised patients 7. Unwilling to participate or to comply with the study requirements, too unwell to take part, or declined to provide consent.

Design outcomes

Primary

Measure	Time frame
KNEE INJURY AND OSTEOARTHRITIS OUTCOME SCORE (KOOS)Timepoint: Baseline & 6 months	—

Secondary

Measure	Time frame
NilTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Birendra Prasad Srivastava

National Institute of Homoeopathy

dr.srivastava61@gmail.com7003178867

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026