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A Study to compare the effects of Intravenous use of Dexmedetomidine versus Saline Intra-Operatively on Recovery of Gastro - Intestinal Function after Elective Gynaecological Surgeries under Spinal Anaesthesia.

A Randomized Controlled Study to compare the effects of Intravenous administration of Dexmedetomidine versus Normal Saline Intra-Operatively on Recovery of Gastro- Intestinal Motility after Elective Gynaecological Surgeries under Spinal Anaesthesia at Sawai Man Singh Medical College, Jaipur. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097505
Enrollment
126
Registered
2025-11-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system

Interventions

Intervention1: Injection Dexmedetomidine.: Intravenous (IV) Dexmedetomidine 0.5 ug/kg in 100 ml of Normal Saline for 1st 10 minutes as the loading dose. For maintenance - Dexmedetomidine 0.5 ug/kg in

Sponsors

Department of Anaesthesia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Female patients. Gynaecological surgeries. Age 18-60years. Surgery duration less than 2hours. American Society of Anaesthesiologist classification 1to 3.

Exclusion criteria

Exclusion criteria: Contra indication for Spinal Anaesthesia. Patients with history of Gastrointestinal dysfunction. Patients with severe bradycardia or hypotension. Patients with history of allergy to Dexmedetomidine and related ingredients. Patients with evidence of any liver or kidney disease. Patients with haemostatic disorders.

Design outcomes

Primary

MeasureTime frame
Mean time to first post operative bowel sounds. Mean time to first post operative faecesTimepoint: At 6 Hours post surgery. At 12 Hours post surgery. At 24 Hours post surgery. At 48 Hours post surgery.

Secondary

MeasureTime frame
Mean VAS score for pain. Mean Modified Ramsay Sedation Score. Proportion of complications.Timepoint: At 6 Hours post surgery. At 12 Hours post surgery. At 24 Hours post surgery. At 48 Hours post surgery.

Countries

India

Contacts

Public ContactPrashant Mathuria

Department of Anaesthesia Sawai Man Singh Medical College

drniharsharma@gmail.com9314044376

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026