Effect of local anaesthesia medicine as steam on heart during nose operations.

A randomized comparative clinical trial to study the effect of 4 percent lignocaine nebulization and 10 percent lignocaine spray on intraoperative hemodynamics for intranasal surgeries under general anaesthesia. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/11/097492

Enrollment

Registered

2025-11-17

Start date

Unknown

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J329- Chronic sinusitis, unspecified Health Condition 2: J329- Chronic sinusitis, unspecified

Interventions

Intervention1: 10 percent lignocaine spray: patients receive 5 puffs of 10 percent topical lignocaine spray in each nostril at 2mg/kg (10mg per puff) 15 minutes before induction in the preoperative

Eligibility

Inclusion criteria

Inclusion criteria: American society of anesthesiologists 1,2. valid written informed consent patient undergoing intranasal surgeries.

Exclusion criteria

Exclusion criteria: American society of Anesthesiologists 3,4 drug allergies bleeding disorders patient refusal pregnancy

Design outcomes

Primary

Measure	Time frame
Changes in Heart rate (HR) and Mean arterial pressure (MAP).Timepoint: o,5,15,30,45,60,90,120,150 minutes	—

Secondary

Measure	Time frame
To compare surgical field score, post operative analgesia.Timepoint: 0,4,12,24 hours	—

Countries

India

Contacts

Public ContactDomala Radhika

esic medical college

domalaradhika@gmail.com9505032812

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026