Comparison of hemodynamic profile between intravenous anaesthesia and intravenous plus gas anesthetic agents anaesthesia in patients with ear nose throat surgeries

Comparison of hemodynamic profile betweenTarget control infusion(tci)- totalintravenous anaesthesia(tiva) and balanced inhalational anaesthesia in otorhinolaryngology surgeries - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/097461

Enrollment

Registered

2025-11-14

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H60-H95- Diseases of the ear and mastoid process Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: ARCOMED pumps: Induction with fentanyl Propofol Vecuronium followed by maintenance with Remifentanil Propofol via ARCOMED pumps for target controlled infusion total intravenous anaesth

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing otorhinolaryngology surgeries that require general anaesthesia with target control infusion total intravenous anaesthesia and balanced anaesthesia American Society of Anesthesiologist physical status 1 and 2

Exclusion criteria

Exclusion criteria: Patients with known case of hypertension renal or hepatic disease Patients with BMI more than 35 Patients on drugs that influence intraoperative hemodynamic stress response Patients who are allergic to any drugs

Design outcomes

Primary

Measure	Time frame
Patients heart rate,systolic blood pressure,diastolic blood pressure,mean arterial blood pressure and end tidal carbon dioxide at the time of induction,during the maintenance phase at 5,10,15,20,25,30 and 45 minutes initially followed by every 30 minutes till 2 hours.Hemodynamic variables will be recorded immediately after extubation and 5 minutes after extubationTimepoint: T(0)-at intubation T(1) at 5 minutes T(2)-at 10 minutes T(3)-at 15 minutes T(4)-at 20 minutes T(5)-at 25 minutes T(6) -at 30 minutes T(7)-at 45 minutes T(8)-at 60 minutes T(9)-at 90 minutes T(10)-at 120 minutes T(E)-immediately after extubation T(E 5)-5 minutes after extubation	—

Measure

Time frame

Patients heart rate,systolic blood pressure,diastolic blood pressure,mean arterial blood pressure and end tidal carbon dioxide at the time of induction,during the maintenance phase at 5,10,15,20,25,30 and 45 minutes initially followed by every 30 minutes till 2 hours.Hemodynamic variables will be recorded immediately after extubation and 5 minutes after extubationTimepoint: T(0)-at intubation T(1) at 5 minutes T(2)-at 10 minutes T(3)-at 15 minutes T(4)-at 20 minutes T(5)-at 25 minutes T(6) -at 30 minutes T(7)-at 45 minutes T(8)-at 60 minutes T(9)-at 90 minutes T(10)-at 120 minutes T(E)-immediately after extubation T(E 5)-5 minutes after extubation

—

Secondary

Measure	Time frame
Postoperative visual analogue score at 1 and 2 hoursTimepoint: T(1) -at 1 hour T(2)-at 2 hours	—

Countries

India

Contacts

Public ContactDr Kumara A B

Shimoga Institute Of Medical Sciences

kumarab_bmc@yahoo.co.in8861958933

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026