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A study to see how raising the legs affects heart function in patients with and without liver disease using an ultrasound of the heart.

Effect of passive leg raising manoeuvre on the change in cardiac output in cirrhotic and noncirrhotic patients using transthoracic echocardiography. A Prospective observational study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/11/097446
Enrollment
30
Registered
2025-11-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K74- Fibrosis and cirrhosis of liver

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Manisha Sura
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -Patients older than 18 years -Compensated cirrhosis -Decompensated cirrhosis -Non- cirrhotic patients

Exclusion criteria

Exclusion criteria: -Unsatisfactory cardiac echogenicity, -Increase in intra-abdominal pressure suspected by clinical context and examination in non-cirrhotic patients. -Patients younger than 18 years, -Body mass index greater than 40 kg/m2 or less than 15 kg/m2, -Aortic valvopathy. -Mitral insufficiency greater than grade 2, Mitral stenosis, or intracardiac shunt

Design outcomes

Primary

MeasureTime frame
To determine changes in CO induced by the PLR manoeuvreTimepoint: Baseline[Before PLR], During PLR, After PLR—

Secondary

MeasureTime frame
Effect of PLR on 1.Heart rate 2.Systolic arterial pressure 3.Diastolic arterial pressure 4.Mean arterial pressure 5.IVCD 6.IVCCI 7.Stroke volume (LVOT –VTI) Timepoint: Baseline[Before PLR], During PLR, After PLR—

Countries

India

Contacts

Public ContactKamal Kajal

Post graduate Institute of Medical Education and Research

kamal.kajal@gmail.com9560412726

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026