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To compare the effect of two drugs used to reverse the effect of drugs used to paralyse using ultrasound scan

COMPARISON OF SUGAMMADEX VERSUS NEOSTIGMINE TO MEASURE RESPIRATORY MUSCLE STRENGTH RECOVERY POST-EXTUBATION IN ADULTS: A RANDOMISED CONTROLLED STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097426
Enrollment
38
Registered
2025-11-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Sugammadex for reversal of neuromuscular blockade after general anaesthesia: In patients undergoing abdominal surgeries under general anaesthesia, neuromuscular blockade is given with I

Sponsors

DrShreya S Hegde
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to give informed consent (ANNEXURE 1) Patients of age 18-60 years. ASA grade 1 & 2(ANNEXURE 2) Patients undergoing abdominal surgeries

Exclusion criteria

Exclusion criteria: American Society of Anesthesiology (ASA) physical status III–IV significant kidney disease (stage 4 kidney disease or higher) significant liver disease (Child-Pugh B or C class) history of chronic obstructive pulmonary disease known or suspected neuromuscular disease arrhythmic disease or use of antiarrhythmic drugs allergy to rocuronium, neostigmine, or sugammadex suspected difficult airway

Design outcomes

Primary

MeasureTime frame
To compare respiratory muscle strength recovery in sugammadex and neostigmine Timepoint: Baseline(before induction of anaesthesia), immediate post extubation, 30 minutes post extubation—

Secondary

MeasureTime frame
To assess time taken from administration of reversal agent to extubation in sugammadex & neostigmine Timepoint: Baseline—

Countries

India

Contacts

Public ContactDr Saraswathi N

Bangalore Medical College and Research Institute.

dr.saraswathi.pmssy@gmail.com9663304834

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026