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Olanzapine for Cancer Anorexia-Cachexia in Carcinoma Cervix: A Prospective Study

Olanzapine to improve cancer anorexia cachexia syndrome in patients with Cervix Carcinoma undergoing Radiotherapy with concurrent Cisplatin – a prospective randomised study - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097381
Enrollment
120
Registered
2025-11-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified

Interventions

Intervention1: Olanzapine: Tab Olanzapine (2.5mg) will be given to intervention arm from start of treatment to the completion of treatment (8 weeks) to prevent Cancer Cachexia Anorexia Syndrome Contro

Sponsors

ABHISHEK BASU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient should be treatment naive, Eastern Cooperative Oncology Group Perfomance Status scale (ECOG PS) should be between 0-2, FIGO STAGE (2021) 1-4, NO MAJOR LIFE THREATENING COMORBODITIES, BASELINE NORMAL BLOOD PARAMETERS

Exclusion criteria

Exclusion criteria: PATIENTS ON LONG TERM STEROIDS, Patients with PSYCHIATRIC ILLNESS, DENIAL OF CONSENT, PATIENTS WITH METABOLIC SYNDROME, PREGANCY AND LACTATION PATIENTS, BMI LESS THAN 18.5

Design outcomes

Primary

MeasureTime frame
To assess the Weight and Appetite change in both the arms at the completion of treatmentTimepoint: At the baseline, at 3rd week and at the end of 8 weeks

Secondary

MeasureTime frame
To assess overal quality of life at the end of treatment in both the armsTimepoint: AT baseline, at 3rd week & at the end of 8 weeks

Countries

India

Contacts

Public ContactAbhishek Basu

Burdwan Medical College and Hospital

drabhishekbasu@yahoo.com9830303459

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026