Health Condition 1: O098- Supervision of other high risk pregnancies
Conditions
Interventions
Intervention1: 150 mg tablet of aspirin orally daily: Oral administration tablet aspirin 150 mg at bedtime from 12 weeks of gestation till 36 completed weeks (total duration of therapy 24 weeks)
Contr
Sponsors
Rampurhat Government Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1.Previous history of preeclampsia 2.chronic hypertension, 3.chronic renal disease, 4. known SLE, 5.known Antiphospholipid syndrome, 6.Type 1 or Type 2 Diabetes, 7.pregnancy by ART and the presence of at least two of the factors associated with a moderate risk of developing preeclampsia like primigravida, age 35 years or more, age less than 19 years, pregnancy interval 10 years or more, multiple pregnancy, BMI 35 or more, 8.Known hypothyroid, 9.known PCOS, 10.anemia with Hb% less than 8 gm%
Exclusion criteria
Exclusion criteria: 1.Active peptic ulcer disease 2.Coagulation disorder 3.Thrombocytopenia 4.History of vaginal bleeding and fetus diagnosed with malformations or aneuploidy in transvaginal ultrasound 5.Known allergy to Aspirin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimating the efficacy of the two doses of aspirin in preventing or delaying the onset and reducing the severity of preeclampsia.Timepoint: After 20 weeks of gestational age | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To study and compare the serious adverse maternal and fetal outcomes in the two treatment groups. Timepoint: After 20 weeks of gestational age;2.To study the nature of and to compare the frequency of drug related adverse events in the two treatment groups.Timepoint: After 20 weeks of gestational age | — |
Countries
India
Contacts
Public ContactPicklu Chaudhuri
Rampurhat Government Medical College
Outcome results
None listed