Evaluation of hyperbaric ropivacaine drug effect when given in single shot spinal anesthesia versus low dose combined spinal epidural anaesthesia in patient groups having cardiac disease and undergoing hip fracture surgery.

Evaluation of efficacy and safety of hyperbaric ropivacaine in single dose spinal versus low dose combined spinal epidural anaesthesia among cardiac patients undergoing hip fracture surgery: A randomized comparative study - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/097360

Enrollment

140

Registered

2025-11-13

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M899- Disorder of bone, unspecified Health Condition 2: W108- Fall (on) (from) other stairs andsteps Health Condition 3: W06- Fall from bed Health Condition 4: W07- Fall from chair Health Condition 5: W15- Fall from cliff Health Condition 6: S720- Fracture of head and neck of femur Health Condition 7: S720- Fracture of head and neck of femur Health Condition 8: S720- Fracture of head and neck of femur Health Condition 9: O- Medical and Surgical Health Condition 10: O- Medical

Interventions

Intervention1: To compare the incidence of hypotension: To determine the incidence of intraoperative hypotension for 150 minutes in patients receiving 0.75% hyperbaric ropivacaine in single shot spina

Eligibility

Inclusion criteria

Inclusion criteria: Patients of 18 years or above, of both sex, ASA grade 2 to 4, having preexisting cardiac disease and undergoing elective hip fracture surgery of expected duration of 2 hours

Exclusion criteria

Exclusion criteria: Any contraindications to spinal anesthesia, allergic to local anesthetics, patient refusal, if patient is converted to GA and pregnancy

Design outcomes

Primary

Measure	Time frame
To compare incidence of intraoperative hypotensionTimepoint: To compare incidence of intraoperative hypotension at baseline, time of induction, at 3, 6,9 12, 15 , 20, 25, 30,35,40,45,50,55,60,75,90,105,120,135 and 150 minutes after induction.	—

Secondary

Measure	Time frame
To compare sensory & motor block characteristicsTimepoint: Sensory & motor block characteristics were noted at 3, 6, 9, 12, 15 & 20 minutes after induction;Hemodynamic profile including systolic BP,diastolic BP,Mean Arterial pressure, Heart Rate & oxygen saturationTimepoint: Hemodynamic vitals noted at baseline, time of induction, 3,6,9,12,15,20,25,30,35,40,45,50,55,60,75,90,105,120,135 & 150 minutes post induction;Adverse cardiac events occurring intraoperatively & postoperativelyTimepoint: Adverse cardiac effects noted for 48 hours postoperatively	—

Measure

Time frame

To compare sensory & motor block characteristicsTimepoint: Sensory & motor block characteristics were noted at 3, 6, 9, 12, 15 & 20 minutes after induction;Hemodynamic profile including systolic BP,diastolic BP,Mean Arterial pressure, Heart Rate & oxygen saturationTimepoint: Hemodynamic vitals noted at baseline, time of induction, 3,6,9,12,15,20,25,30,35,40,45,50,55,60,75,90,105,120,135 & 150 minutes post induction;Adverse cardiac events occurring intraoperatively & postoperativelyTimepoint: Adverse cardiac effects noted for 48 hours postoperatively

—

Countries

India

Contacts

Public ContactDr Deeksha Chandra

R.N.T medical college

Uditanaithani@gmail.com9829414752

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026