Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: Edinora prime tooth paste: Instructions-Advised to use the tooth paste and brush daily for two minutes using modified bass technique.
Ingredients-Glycyrrhiza glabra, Embilica officina
Sponsors
Aparna M Nair
Eligibility
Inclusion criteria
Inclusion criteria: 1. Generalized stage III periodontitis patients according to criteria given by American Academy of Periodontology 2017 classification. 2. Periodontal disease as indicated by at least 1 site in each quadrant with Pocket Depth (PD) in the range of 6 -8 mm with Bleeding on Probing (BOP) 3. Those who are willing to participate in the study
Exclusion criteria
Exclusion criteria: 1. Pregnancy or lactation 2. Subjects currently undergoing orthodontic therapy 3. Inflammatory conditions associated with skin and oral mucosa 4. The use of prescription antibiotics, mouth rinse, corticosteroids, or anti- inflammatory drugs within the past three months 5. Recent periodontal therapy within the last six months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage reduction in number of periodontal pockets with PPD ≥ 4mm with bleeding on probing in group treated with Edinora dentifrice compared to control groupTimepoint: At 3 months & 9 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Change in oral microbiome profile in group treated with Edinora dentifrice compared to control group 2. Reduction in the salivary IL-1β levels measured using ELISA in group treated with Edinora dentifrice compared to control group 3. Change in salivary lipoxin A4 measured using ELISA in group treated with Edinora dentifrice compared to control group Timepoint: At 3 months & 9 months | — |
Countries
India
Contacts
Public ContactDr Aparna M Nair
Outcome results
None listed