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A comparative study of Yoga-enhanced Platelet-Rich Plasma and Conventional Platelet-Rich Plasma therapy in improving growth factor levels and knee function in early osteoarthritis.

Y-PRP Trial : Yoga enhanced PRP vs Conventional PRP- Growth factor assessment and functional outcomes in early knee osteoarthritis - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097338
Enrollment
80
Registered
2025-11-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

Intervention1: Intra articular injection of PRP in knees: The injection will be given on the same day of preparation preferably within 30 minutes of preparation. The patients will be made to lie down

Sponsors

CCRYN
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Symptomatic Primary OA Knee OA classified as Grade 1 & 2 who have responded to conservative treatment for 6 months

Exclusion criteria

Exclusion criteria: Secondary OA Grade 3& 4 OA immunocompromised status or uncontrolled diabetes bronchial Asthma or known cardiac disease Symptomatic OA affecting joint other than knees Recent 6 month intra articular steroids anti coagulation therapy active or previous infections unwilling to follow exercise protocol/ not consenting for intervention

Design outcomes

Primary

MeasureTime frame
To study the effect of specific yoga protocol on the cell count & growth factor yield of PRPTimepoint: Check whether PRP has better Growth Factor post yoga therapy

Secondary

MeasureTime frame
To compare functional outcomes in terms of WOMAC, VAS, DASS 21 score between conventional & yoga enhanced PRPTimepoint: At 6 weeks, 3 months & 6 months

Countries

India

Contacts

Public ContactA Ramachandra Dora

PGIMER

rjintu001@gmail.com9437374275

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026