A study comparing Remifentanil and Lidocaine as interventions to control Blood Pressure and Heart Rate during Intubation in study participants, with the main outcome being how effectively they keep these vital signs stable

Comparison of Remifentanil and Lidocaine in attenuation of haemodynamic responses during intubation in patients undergoing general anesthesia - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/097306

Enrollment

Registered

2025-11-13

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Injection REMIFENTANIL: One dose of INJ REMIFENTANIL 1mcg/kg Intravenously will be injected 90 seconds before intubation Control Intervention1: INJ LIDOCAINE: One dose of INJ LIDOCAINE

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1&2 Undergoing elective surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: Known allergy to study drugs History of cardiovascular disease Patients on beta blockers or anti hypertensive medication Difficult airway or anticipated difficult intubation Emergency surgeries

Design outcomes

Primary

Measure	Time frame
To compare the increase of heart rate between two groupsTimepoint: T1 - Baseline T2 - 90 seconds after administration of study drug T3 - 1 minute after intubation T4 - 3 minutes after intubation	—

Secondary

Measure	Time frame
Two record BP.Timepoint: T1-BASE LINE T2-After 90 SECONDS T3-1 MINUTE AFTER INTUBATION T4-3 MINUTES AFTER INTUBATION	—

Countries

India

Contacts

Public ContactDrRavichandra Dodawad

ESIC medical college

dr.ravichandra.dodawad@esic.nic.in9986514152

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026