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A study among patients undergoing tooth extraction to compare bone healing using bone graft alone and Bone graft enriched with Vitamin D3.

Comparative evaluation of efficacy of DFDBA and DFDBA enriched with Vitamin D3 in alveolar socket preservation A Clinical Radiographic and Histologic study - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097258
Enrollment
60
Registered
2025-11-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K068- Other specified disorders of gingiva and edentulous alveolar ridge

Interventions

Intervention1: DFDBA with Vitamin D3 gel: A full thickness mucoperiosteal flap with two vertical incisions will be reflected and tooth extraction will be carried out. After debridement of socket, DFDB

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients above the age of 18 years, Patients with no medical history that contraindicates the surgical procedure, adequate space for a satisfactory implant restoration. Only maxillary and mandibular premolars or molars indicated for extraction, and replacement with dental implant.

Exclusion criteria

Exclusion criteria: Patients with a history of any systemic diseases that might impair bone metabolism, Patients that exhibited poor oral hygiene, Patients demonstrating a buccal dehiscence of more than 25% of the length of the tooth, Edentulous spaces adjacent to the tooth indicated for extraction, Patients who are smokers, Patients on antiresorptive therapy (as bisphosphonates), and Pregnancy and nursing period, psychiatric conditions, and oncologically relevant diseases.

Design outcomes

Primary

MeasureTime frame
bone formation in Alveolar socketTimepoint: Baseline and 6 Months

Secondary

MeasureTime frame
Soft tissue healing Buccolingual width of alveolar ridge Vertical ridge resorption Percentage of vital bone formationTimepoint: Baseline and 6 months

Countries

India

Contacts

Public ContactDr Prachi Rathi

Ranjeet Deshmukh Dental College and Research Centre Nagpur

prachi.rathi.9@gmail.com9975216388

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026