Health Condition 1: D50-D89- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Intervention4: NIL observational study: NIL
Sponsors
Kasturba Medical College Manipal Academy of Higher education manipal karnataka india
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients admitted in ICU having bew onset thrombocytopenia
Exclusion criteria
Exclusion criteria: 1)Low platelet count because of major hemorrhage 2)Known cases of platelet function disorders. 3)Patients on antiplatelet drugs 4)Family history of bleeding disorders 5)Patients with chronic liver/kidney disease 6)Known case of bleeding disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To understand the variation in platelet transfusion requirement in critically ill patients through individualized transfusion support.Timepoint: At the time of each episode of thrombocytopenia or before platelet transfusion (within 24 hours of ICU admission or thrombocytopenia detection) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Establishing the causes of thrombocytopenia in critical care. 2) Analyzing the utility of thrombo-elastography in determining the platelet transfusion requirement in thrombocytopenia in critical care. 3) Identifying the predictability of platelet transfusions from thrombo-elastography & platelet indices parameters 4) To determine the indications & requirements for platelet transfusion in these cases. Timepoint: 1 at the time of diagnosis of thrombocytopenia day 0 or day1 of ICU stay 2 during ICU stay monitored daily or at each transfusion event 3 At the end of ICU stay or discharge | — |
Countries
India
Contacts
Public ContactDr Anderson David Lyngdoh
Kasturba Medical College Manipal Academy of Higher Education
Outcome results
None listed