Health Condition 1: J988- Other specified respiratory disorders
Conditions
Interventions
Intervention1: contrast enhanced ultrsaound guided biopsy of thoracic lesions: The included patients after randomisation will be included in the intervention group.
Procedure details of CEUS-guided
Sponsors
Intramural fund from AIIMS Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adults with equal to or more than 18 years of age presenting to the Pulmonary OPD or IPD with peripheral pulmonary lesions, pleural lesions (pleural thickening or pleural nodularity) and undiagnosed pleural effusion having a clinical indication for trans-thoracic biopsy. 2. The lesions should have been confirmed on the chest computed tomography and detectable by chest ultrasound. 3. The minimum size of lesions should be at least 10 mm or more on ultrasound imaging. For undiagnosed pleural effusion, the pleural thickening should be at least 10 mm or more, which is considered suitable for obtaining a biopsy
Exclusion criteria
Exclusion criteria: 1. Any contraindications to biopsy (low platelet count, coagulation defects or bleeding diathesis, clinical instability or unsafe location of biopsy) 2. Patients refusing consent 3. Any contraindication to ultrasound contrast agents such as a prior history of an allergic reaction, pregnancy, severe pulmonary hypertension or presence of right-to-left cardiac shunts
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the diagnostic yield of CEUS-guided biopsy with conventional USG-guided biopsy in peripheral pulmonary and pleural lesions.Timepoint: twelve months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the diagnostic yield of CEUS-guided biopsy with conventional USG-guided biopsy in undiagnosed pleural effusions.Timepoint: twelve months;2. To assess the factors associated with a negative yield in CEUS-guided biopsyTimepoint: twelve months | — |
Countries
India
Contacts
Public ContactMahismita Patro
AIIMS BHUBANESWAR
Outcome results
None listed