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Comparing two simple blood measures to predict recovery in children with severe infection

Comparison of blood lactate-to-bicarbonate ratio versus blood lactate alone for predicting outcomes in children with septic shock - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/11/097184
Enrollment
130
Registered
2025-11-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A419- Sepsis, unspecified organism

Interventions

Intervention1: Nil: Nil Intervention2: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

UNIVERSITY COLLEGE OF MEDICAL SCIENCES GTB HOSPITAL INSTITUTE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children diagnosed with septic shock of age 1 to 12 years

Exclusion criteria

Exclusion criteria: Children with known metabolic disorders or inborn errors of metabolism. Children with chronic liver or kidney disease. Children on immunosuppressive therapy or known malignancy.

Design outcomes

Primary

MeasureTime frame
To compare in-hospital mortality (defined as death during the hospital admission for septic shock) of children with septic shock using blood lactate-to-bicarbonate ratio versus blood lactate alone as predictors.Timepoint: At baseline

Secondary

MeasureTime frame
To correlate length of hospital stay (in days) ,requirement for mechanical ventilation and duration of mechanical ventilation to blood lactate-to-bicarbonate ratio and blood lactate alone.Timepoint: At time of discharge or death;To correlate p-SOFA score at baseline to blood lactate-to-bicarbonate ratio and blood lactate alone.Timepoint: Within 6 hours of admission

Countries

India

Contacts

Public ContactDr Jyoti Antil

University College of Medical Sciences

manish_2710@yahoo.com9625900829

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026