None listed
Conditions
Interventions
Intervention1: Nalbuphine: Single-shot Nalbuphine 10mg will be given along with 0.125% Bupivacaine diluted to 10 mL in normal saline via epidural catheter, postoperatively when sensory level drops to
Sponsors
Vinayaka Missions Kirupananda Variyar Medical College & Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA Physical Status 1 and 2 2. Patients undergoing elective infraumbilical surgeries under combined spinal-epidural anaesthesia 3. Patients willing to provide informed consent
Exclusion criteria
Exclusion criteria: 1. Patients on opioids, tricyclic antidepressants, or alpha-2 agonists 2. Patients with coagulation defects and patients on anticoagulants 3. Patients with neuromuscular disorders 4. Patients with disease and deformities of spinal cord 5. Patients allergic to local anaesthetic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of postoperative analgesia, defined as the time from epidural drug administration to the first request for rescue analgesiaTimepoint: 0 min, 5 min, 10 min, 15 min, 20 min, 25 min, 30 min, 1 hr, 1.5 hr, 2 hr, 2.5 hr, 3 hr, 3.5 hr, 4 hr, 4.5 hr, 5 hr, 5.5 hr, 6 hr, 7 hr, 8 hr, 10 hr, 12 hr after administering drug | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scores at rest & movement using the Visual Analog Scale (VAS) at predefined time intervalsTimepoint: From 0 min of administering drug & 5 min, 10 min, 15 min, 20 min, 25 min, 30 min, 1 hr, 1.5 hr, 2 hr, 2.5 hr, 3 hr, 3.5 hr, 4 hr, 4.5 hr, 5 hr, 5.5 hr, 6 hr, 7 hr, 8 hr, 10 hr, 12 hr after administering drug;Incidence of side effects & derangement in haemodynamic parametersTimepoint: From 0 min of administering drug & 5 min, 10 min, 15 min, 20 min, 25 min, 30 min, 1 hr, 1.5 hr, 2 hr, 2.5 hr, 3 hr, 3.5 hr, 4 hr, 4.5 hr, 5 hr, 5.5 hr, 6 hr, 7 hr, 8 hr, 10 hr, 12 hr after administering drug | — |
Countries
India
Contacts
Public ContactDr Aupama M
Vinayaka Missions Kirupananda Variyar Medical College and Hospitals
Outcome results
None listed